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LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer

BACKGROUND: LncRNA TUG1 has been reported to be highly expressed in CRC samples and cells and promoted metastasis by affecting EMT, indicating a poor prognosis for colorectal cancer (CRC). In this study, we determined the underlying mechanism for tumor oncogenesis of lncRNA TUG1 in CRC metastasis. M...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Sun, Junfeng, Hu, Jiyi, Wang, Guojun, Yang, Zhen, Zhao, Chunlin, Zhang, Xiefu, Wang, Jiaxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960095/
https://ncbi.nlm.nih.gov/pubmed/29776371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0771-x
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