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Synthesis of (+)-Pancratistatins via Catalytic Desymmetrization of Benzene

A concise synthesis of (+)-pancratistatin and (+)-7-deoxypancratistatin from benzene using an enantioselective, dearomative carboamination strategy has been achieved. This approach, in combination with the judicious choice of subsequent olefin-type difunctionalization reactions, permits rapid and co...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Hernandez, Lucas W., Pospech, Jola, Klöckner, Ulrich, Bingham, Tanner W., Sarlah, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960067/
https://ncbi.nlm.nih.gov/pubmed/29059521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10351
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