Fast and accurate quantitative organic acid analysis with LC-QTOF/MS facilitates screening of patients for inborn errors of metabolism

Since organic acid analysis in urine with gaschromatography-mass spectrometry (GC-MS) is a time-consuming technique, we developed a new liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF/MS) method to replace the classical analysis for diagnosis of inborn errors of metabolism...

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Detalhes bibliográficos
Publicado no:J Inherit Metab Dis
Main Authors: Körver-Keularts, Irene M. L. W., Wang, Ping, Waterval, Huub W. A. H., Kluijtmans, Leo A. J., Wevers, Ron A., Langhans, Claus-Dieter, Scott, Camilla, Habets, Daphna D. J., Bierau, Jörgen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959959/
https://ncbi.nlm.nih.gov/pubmed/29435781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-017-0129-0
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