Chronic restraint stress during withdrawal increases vulnerability to drug priming-induced cocaine seeking via a dopamine D1-like receptor-mediated mechanism

BACKGROUND: A major obstacle in the treatment of individuals with cocaine addiction is their high propensity for relapse. Although the clinical scenario of acute stress-induced relapse has been well studied in animal models, few pre-clinical studies have investigated the role of chronic stress in re...

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Pubblicato in:Drug Alcohol Depend
Autori principali: Ball, Kevin T., Stone, Eric, Best, Olivia, Collins, Tyler, Edson, Hunter, Hagan, Erin, Nardini, Salvatore, Neuciler, Phelan, Smolinsky, Michael, Tosh, Lindsay, Woodlen, Kristin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959797/
https://ncbi.nlm.nih.gov/pubmed/29705546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2018.03.024
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