White matter microstructure, white matter lesions, and hypertension: An examination of early surrogate markers of vascular-related brain change in midlife

OBJECTIVE: We examined imaging surrogates of white matter microstructural abnormalities which may precede white matter lesions (WML) and represent a relevant marker of cerebrovascular injury in adults in midlife. METHODS: In 698 community-dwelling adults (mean age 50 years ±3.5 SD) from the Coronary...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Haight, Thaddeus, Nick Bryan, R., Erus, Guray, Hsieh, Meng-Kang, Davatzikos, Christos, Nasrallah, Ilya, D'Esposito, Mark, Jacobs, David R., Lewis, Cora, Schreiner, Pamela, Sidney, Stephen, Meirelles, Osorio, Launer, Lenore J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959740/
https://ncbi.nlm.nih.gov/pubmed/29785359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.02.032
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