Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery

Identification of optimal transcription factor expression patterns to direct cellular differentiation along a desired pathway presents significant challenges. We demonstrate massively combinatorial screening of temporally-varying mRNA transcription factors to direct differentiation of neural progeni...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Azimi, Sayyed M, Sheridan, Steven D, Ghannad-Rezaie, Mostafa, Eimon, Peter M, Yanik, Mehmet Fatih
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2018
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959718/
https://ncbi.nlm.nih.gov/pubmed/29714688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31922
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