AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells

Phosphorylation is a major type of post-translational modification, which can influence the cellular physiological function. ATG4B, a key macroautophagy/autophagy-related protein, has a potential effect on the survival of tumor cells. However, the role of ATG4B phosphorylation in cancers is still un...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Ni, Zhenhong, He, Jintao, Wu, Yaran, Hu, Changjiang, Dai, Xufang, Yan, Xiaojing, Li, Bo, Li, Xinzhe, Xiong, Haojun, Li, Yuming, Li, Song, Xu, Liang, Li, Yongsheng, Lian, Jiqin, He, Fengtian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Papers - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959332/
https://ncbi.nlm.nih.gov/pubmed/29165041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1407887
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