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Epithelial ERα Is Dispensable for the Development of Estrogen–Induced Cervical Neoplastic Diseases
Human papillomavirus (HPV) is required but not sufficient for cervical carcinoma (CxCa). Estradiol (E(2)) promotes CxCa development in K14E7 transgenic mice expressing the HPV16 E7 oncoprotein under the control of the keratin 14 (K14) promoter. E(2) mainly works through estrogen receptor α (ERα). Ho...
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| 發表在: | J Pathol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959269/ https://ncbi.nlm.nih.gov/pubmed/29532467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5069 |
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