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RNAi drives nonreciprocal translocations at eroding chromosome ends to establish telomere-free linear chromosomes
The identification of telomerase-negative HAATI (heterochromatin amplification-mediated and telomerase-independent) cells, in which telomeres are superseded by nontelomeric heterochromatin tracts, challenged the idea that canonical telomeres are essential for chromosome linearity and raised crucial...
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| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959237/ https://ncbi.nlm.nih.gov/pubmed/29654060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.311712.118 |
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