Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy

INTRODUCTION: Kidney fibrosis is the main pathologic change in diabetic nephropathy (DN), which is the major cause of end-stage renal disease. Current therapeutic strategies slow down but cannot reverse the progression of renal dysfunction in DN. Plant-derived bioactive peptides in foodstuffs are wi...

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Publicado en:Drug Des Devel Ther
Autores principales: Zhang, Mingyan, Yan, Zhibin, Bu, Lili, An, Chunmei, Wang, Dan, Liu, Xin, Zhang, Jianfeng, Yang, Wenle, Deng, Bochuan, Xie, Junqiu, Zhang, Bangzhi
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958891/
https://ncbi.nlm.nih.gov/pubmed/29795979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S162288
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