Vascular endothelial specific IL-4Rα–ABL1 kinase signaling axis regulates severity of IgE-mediated anaphylactic reactions

BACKGROUND: Severe IgE-mediated, food-induced anaphylactic reactions are characterized by pulmonary venous vasodilatation and fluid extravasation, which is thought to lead to the life-threatening anaphylactic phenotype. The underlying immunological and cellular processes involved in driving fluid ex...

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Bibliografski detalji
Izdano u:J Allergy Clin Immunol
Glavni autori: Yamani, Amnah, Wu, David, Waggoner, Lisa, Noah, Taeko, Koleske, Anthony J., Finkelman, Fred, Hogan, Simon P.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957775/
https://ncbi.nlm.nih.gov/pubmed/29157947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.08.046
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