Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

The medial prefrontal cortex (mPFC) has been implicated in the extinction of emotional memories, including conditioned fear. Here we show that ventral hippocampal (vHPC) projections to the infralimbic (IL) cortex recruit parvalbumin (PV)-expressing interneurons to counter the expression of extinguis...

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Bibliographic Details
Published in:Nat Neurosci
Main Authors: Marek, Roger, Jin, Jingji, Goode, Travis D., Giustino, Thomas F., Wang, Qian, Acca, Gillian M., Holehonnur, Roopashri, Ploski, Jonathan E., Fitzgerald, Paul J., Lynagh, Timothy P., Lynch, Joseph W., Maren, Stephen, Sah, Pankaj
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957529/
https://ncbi.nlm.nih.gov/pubmed/29403033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0073-9
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