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The DSL ligand APX-1 is required for normal ovulation in C. elegans

DSL ligands activate the Notch receptor in many cellular contexts across metazoa to specify cell fate. In addition, Notch receptor activity is implicated in post-mitotic morphogenesis and neuronal function. In C. elegans, the DSL family ligand APX-1 is expressed in a subset of cells of the proximal...

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Bibliographic Details
Published in:Dev Biol
Main Authors: McGovern, Marie, Castaneda, Perla Gisela, Pekar, Olga, Vallier, Laura G., Cram, Erin J., Hubbard, E. Jane Albert
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957500/
https://ncbi.nlm.nih.gov/pubmed/29371032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.01.009
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