Inactivation of bpsl1039-1040 ATP-binding cassette transporter reduces intracellular survival in macrophages, biofilm formation and virulence in the murine model of Burkholderia pseudomallei infection

Burkholderia pseudomallei, a gram-negative intracellular bacillus, is the causative agent of a tropical infectious disease called melioidosis. Bacterial ATP-binding cassette (ABC) transporters import and export a variety of molecules across bacterial cell membranes. At present, their significance in...

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Udgivet i:PLoS One
Main Authors: Pinweha, Peechanika, Pumirat, Pornpan, Cuccui, Jon, Jitprasutwit, Niramol, Muangsombut, Veerachat, Srinon, Varintip, Boonyuen, Usa, Thiennimitr, Parameth, Vattanaviboon, Paiboon, Cia, Felipe, Willcocks, Sam, Bancroft, Gregory J., Wren, Brendan W., Korbsrisate, Sunee
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957425/
https://ncbi.nlm.nih.gov/pubmed/29771915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196202
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