Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig

There is increasing evidence that induction of local immune responses is a key component of effective vaccines. For respiratory pathogens, for example tuberculosis and influenza, aerosol delivery is being actively explored as a method to administer vaccine antigens. Current animal models used to stu...

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Publicado en:PLoS Pathog
Autores principales: Tungatt, Katie, Dolton, Garry, Morgan, Sophie B., Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D., Porter, Emily, Szomolay, Barbara, Montoya, Maria, Hammond, John A., Miles, John J., Cole, David K., Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J., Charleston, Bryan, Tchilian, Elma, Sewell, Andrew K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957346/
https://ncbi.nlm.nih.gov/pubmed/29772011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007017
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