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Effects of Alterations of the E. coli Lipopolysaccharide Layer on Membrane Permeabilization Events Induced by Cecropin A

The outermost layer of Gram negative bacteria is composed of a lipopolysaccharide (LPS) network that forms a dense protective hydrophilic barrier against entry of hydrophobic drugs. At low μM concentrations, a large family of cationic polypeptides known as antimicrobial peptides (AMPs) is able to pe...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Agrawal, Anurag, Weisshaar, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957292/
https://ncbi.nlm.nih.gov/pubmed/29684333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.04.009
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