Th2 cytokines and asthma — Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists

Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of eosinophil transmigration across endothelium, mucus secretion, and differentiation of T helper type 2 lym...

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Detalhes bibliográficos

Publicado no:	Respir Res
Principais autores:	Steinke, John W, Borish, Larry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2001
Assuntos:	Review
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11686867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/rr40
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