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Induction of anti-PF4/heparin antibodies after arthroplasty for rheumatic diseases
Heparin-induced thrombocytopenia (HIT) is an immune complication of heparin therapy caused by antibodies to complexes of platelet factor 4 (PF4) and heparin. These pathogenic antibodies against PF4/heparin bind and activate cellular FcγRIIa on platelets to induce a hypercoagulable state culminating...
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| Publicado no: | Fukushima J Med Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Fukushima Society of Medical Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956084/ https://ncbi.nlm.nih.gov/pubmed/29628468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5387/fms.2018-06 |
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