High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease

Progress in clinical development of magnetic resonance imaging (MRI) substrate-sensors of enzymatic activity has been slow partly due to the lack of human efficacy data. We report here a strategy that may serve as a shortcut from bench to bedside. We tested ultra high-resolution 7T MRI (µMRI) of hum...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wadghiri, Youssef Z., Hoang, Dung Minh, Leporati, Anita, Gounis, Matthew J., Rodríguez-Rodríguez, Aurora, Mazzanti, Mary L., Weaver, John P., Wakhloo, Ajay K., Caravan, Peter, Bogdanov, Alexei A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956082/
https://ncbi.nlm.nih.gov/pubmed/29769642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25804-y
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