Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma

Clustered miRNAs can affect functioning of downstream pathways due to possible coordinated function. We observed 78–88% of the miR-379/miR-656 cluster (C14MC) miRNAs were downregulated in three sub-types of diffuse gliomas, which was also corroborated with analysis from The Cancer Genome Atlas (TCGA...

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Udgivet i:Sci Rep
Main Authors: Nayak, Subhashree, Aich, Meghali, Kumar, Anupam, Sengupta, Suman, Bajad, Prajakta, Dhapola, Parashar, Paul, Deepanjan, Narta, Kiran, Purkrait, Suvendu, Mehani, Bharati, Suri, Ashish, Chakraborty, Debojyoti, Mukhopadhyay, Arijit, Sarkar, Chitra
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955984/
https://ncbi.nlm.nih.gov/pubmed/29769662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26000-8
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