Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is one of the leading causes of chronic liver disease worldwide. However, details of pathogenetic mechanisms remain unknown. Deletion of both p62/Sqstm1 and Nrf2 genes spontaneously led to the development of NASH in mice fed a normal chow and was associated with l...

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Dades bibliogràfiques
Publicat a:Exp Anim
Autors principals: Akiyama, Kentaro, Warabi, Eiji, Okada, Kosuke, Yanagawa, Toru, Ishii, Tetsuro, Kose, Katsumi, Tokushige, Katsutoshi, Ishige, Kazunori, Mizokami, Yuji, Yamagata, Kenji, Onizawa, Kojiro, Ariizumi, Shun-ichi, Yamamoto, Masakazu, Shoda, Junichi
Format: Artigo
Idioma:Inglês
Publicat: Japanese Association for Laboratory Animal Science 2017
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Original
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955752/
https://ncbi.nlm.nih.gov/pubmed/29276215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.17-0112
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