Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is one of the leading causes of chronic liver disease worldwide. However, details of pathogenetic mechanisms remain unknown. Deletion of both p62/Sqstm1 and Nrf2 genes spontaneously led to the development of NASH in mice fed a normal chow and was associated with l...

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Publicado no:Exp Anim
Main Authors: Akiyama, Kentaro, Warabi, Eiji, Okada, Kosuke, Yanagawa, Toru, Ishii, Tetsuro, Kose, Katsumi, Tokushige, Katsutoshi, Ishige, Kazunori, Mizokami, Yuji, Yamagata, Kenji, Onizawa, Kojiro, Ariizumi, Shun-ichi, Yamamoto, Masakazu, Shoda, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Association for Laboratory Animal Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955752/
https://ncbi.nlm.nih.gov/pubmed/29276215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.17-0112
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