Treatment with specific soluble factors promotes the functional maturation of transcription factor-mediated, pancreatic transdifferentiated cells

Pancreatic lineage-specific transcription factors (TFs) display instructive roles in converting adult cells to endocrine pancreatic cells through a process known as transdifferentiation. However, little is known about potential factors capable of accelerating transdifferentiation following transduct...

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Bibliographic Details
Published in:PLoS One
Main Authors: Motoyama, Hiroaki, Kobayashi, Akira, Yokoyama, Takahide, Shimizu, Akira, Sakai, Hiroshi, Notake, Tsuyoshi, Fukushima, Kentaro, Miyagawa, Shin-ichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955553/
https://ncbi.nlm.nih.gov/pubmed/29768476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197175
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