Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas

Dormant cancer cells are starvation-resistant leading to problems in the management of cancer. In renal cell carcinomas (RCCs), starvation-resistant cells are resistant to various currently available therapies. However, targeting hypoxia inducible factor 2-alpha (HIF2-alpha) induces cell death in do...

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Vydáno v:Oncotarget
Hlavní autoři: Isono, Takahiro, Chano, Tokuhiro, Yoshida, Tetsuya, Kageyama, Susumu, Kawauchi, Akihiro, Yonese, Junji, Yuasa, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955402/
https://ncbi.nlm.nih.gov/pubmed/29796174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25214
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