Naïve B cells reduce fungal dissemination in Cryptococcus neoformans infected Rag1(−/−) mice

IgM and B-1 cell deficient mice exhibit early C. neoformans dissemination from lungs to brain, but a definitive role for B cells in conferring resistance to C. neoformans dissemination has not been established. To address this question, we developed an intranasal (i.n.) C. neoformans infection model...

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Foilsithe in:Virulence
Main Authors: Dufaud, Chad, Rivera, Johanna, Rohatgi, Soma, Pirofski, Liise-anne
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955176/
https://ncbi.nlm.nih.gov/pubmed/28837391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1370529
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