Bufalin inhibits gastric cancer invasion and metastasis by down-regulating Wnt/ASCL2 expression

Achaete-scute-like 2 (ASCL2) is a transcription factor containing a basic helix-loop-helix (bHLH) domain and is a downstream target of Wnt signaling in intestinal stem cells. Bufalin is the primary active ingredient in Chan Su, a traditional Chinese medicine obtained from the skin and parotid venom...

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Udgivet i:Oncotarget
Main Authors: Wang, Jie, Cai, Han, Xia, Yue, Wang, Shiying, Xing, Likai, Chen, Chao, Zhang, Yong, Xu, Jie, Yin, Peihao, Jiang, Yiming, Zhao, Ronghua, Zuo, Qingshong, Chen, Teng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955089/
https://ncbi.nlm.nih.gov/pubmed/29805736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24157
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