Signal Transducer and Activator of Transcription 1 Regulates Multiwalled Carbon Nanotube–induced Pulmonary Fibrosis in Mice via Suppression of Transforming Growth Factor-β1 Production and Signaling

Rationale: Multiwalled carbon nanotubes (MWCNTs) are a potential risk for pulmonary fibrosis because of their fiber-like shape; other physicochemical features, such as rigidity, could also confer fibrogenicity. The signal transducer and activator of transcription 1 (STAT1) is an important antifibrog...

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Publié dans:Ann Am Thorac Soc
Auteurs principaux: Duke, Katherine S., Taylor, Alexia J., Ihrie, Mark D., Shipkowski, Kelly A., Needham, Erinn C., Bonner, James C.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2018
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955037/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201707-588MG
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