Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions

BACKGROUND: We developed a classifier using RNA sequencing data that identifies the usual interstitial pneumonia (UIP) pattern for the diagnosis of idiopathic pulmonary fibrosis. We addressed significant challenges, including limited sample size, biological and technical sample heterogeneity, and re...

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Dades bibliogràfiques
Publicat a:BMC Genomics
Autors principals: Choi, Yoonha, Liu, Tiffany Ting, Pankratz, Daniel G., Colby, Thomas V., Barth, Neil M., Lynch, David A., Walsh, P. Sean, Raghu, Ganesh, Kennedy, Giulia C., Huang, Jing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954282/
https://ncbi.nlm.nih.gov/pubmed/29764379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4467-6
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