Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections

Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to prevent and treat these potentially lethal infections. Stimulation of intrinsic lung defenses via inhalation of synergistically acting Toll-like receptor (TLR) agonists protects mice broadly against pneumonia, inc...

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Publicado no:mBio
Main Authors: Kirkpatrick, Carson T., Wang, Yongxing, Leiva Juarez, Miguel M., Shivshankar, Pooja, Pantaleón García, Jezreel, Plumer, Alexandria K., Kulkarni, Vikram V., Ware, Hayden H., Gulraiz, Fahad, Chavez Cavasos, Miguel A., Martinez Zayes, Gabriela, Wali, Shradha, Rice, Andrew P., Liu, Hongbing, Tour, James M., Sikkema, William K. A., Cruz Solbes, Ana S., Youker, Keith A., Tuvim, Michael J., Dickey, Burton F., Evans, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954225/
https://ncbi.nlm.nih.gov/pubmed/29764948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00696-18
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