Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice

Hematopoietic stem cells (HSCs) continuously replenish all blood cell types through a series of differentiation steps and repeated cell divisions that involve the generation of lineage-committed progenitors. However, whether cell division in HSCs precedes differentiation is unclear. To this end, we...

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Pubblicato in:Nat Commun
Autori principali: Grinenko, Tatyana, Eugster, Anne, Thielecke, Lars, Ramasz, Beáta, Krüger, Anja, Dietz, Sevina, Glauche, Ingmar, Gerbaulet, Alexander, von Bonin, Malte, Basak, Onur, Clevers, Hans, Chavakis, Triantafyllos, Wielockx, Ben
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954009/
https://ncbi.nlm.nih.gov/pubmed/29765026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04188-7
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