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B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation
B cells provide humoral immunity by differentiating into antibody-secreting plasma cells, a process that requires cellular division and is linked to DNA hypomethylation. Conversely, little is known about how de novo deposition of DNA methylation affects B cell fate and function. Here we show that ge...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953949/ https://ncbi.nlm.nih.gov/pubmed/29765016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04234-4 |
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