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A single-molecule flow platform for the quantification of biomolecules attached to single nanoparticles

We describe here a flow platform for quantifying the number of biomolecules on individual fluorescent nanoparticles. The platform combines line-confocal fluorescence detection with near nanoscale channels (1–2 µm in width and height) to achieve high single-molecule detection sensitivity and throughp...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Jung, Seung-Ryoung, Han, Rui, Sun, Wei, Jiang, Yifei, Fujimoto, Bryant S., Yu, Jiangbo, Kuo, Chun-Ting, Rong, Yu, Zhou, Xing-Hua, Chiu, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953847/
https://ncbi.nlm.nih.gov/pubmed/29672026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b00024
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