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Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress
Malignant transformation can result in melanoma cells that resemble different stages of their embryonic development. Our gene expression analysis of human melanoma cell lines and patient tumors revealed that melanoma follows a two-dimensional differentiation trajectory that can be sub-classified int...
שמור ב:
| הוצא לאור ב: | Cancer Cell |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953834/ https://ncbi.nlm.nih.gov/pubmed/29657129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.017 |
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