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Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers

BACKGROUND: CW002 is an investigational non-depolarizing, neuromuscular blocking agent with a rapid onset and intermediate duration of action in animals. This is a single ascending dose, healthy subject study exploring tolerability, pharmacokinetics, and potency. METHODS: Population PK (PopPK) and P...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Kaullen, Josh D., Owen, Joel S., Brouwer, Kim L.R., Heerdt, Paul M., Lien, Cynthia A., Savarese, John J., Schmith, Virginia D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953789/
https://ncbi.nlm.nih.gov/pubmed/29494403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002157
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