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Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins

Although the human gut microbiome plays a prominent role in xenobiotic transformation, most of the genes and enzymes responsible for this metabolism are unknown. Recently, we linked the two-gene ‘cardiac glycoside reductase’ (cgr) operon encoded by the gut Actinobacterium Eggerthella lenta to inacti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Koppel, Nitzan, Bisanz, Jordan E, Pandelia, Maria-Eirini, Turnbaugh, Peter J, Balskus, Emily P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953540/
https://ncbi.nlm.nih.gov/pubmed/29761785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33953
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