Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia

BACKGROUND: There is evidence that maternal genotypes in folate-related genes are associated with pediatric acute lymphoblastic leukemia (ALL) independent of offspring genotype. We evaluated the relationship between maternal genotypes in methionine synthase (MTR) and DNA methylation status in ALL to...

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Publicat a:PLoS One
Autors principals: Schraw, Jeremy M., Yiu, Teresa T., Lupo, Philip J., Tsavachidis, Spiridon, Rau, Rachel, Bondy, Melissa L., Rabin, Karen R., Shen, Lanlan, Scheurer, Michael E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953491/
https://ncbi.nlm.nih.gov/pubmed/29763473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197408
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