Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular Carcinoma

BACKGROUND: Patients with cirrhosis are at high risk of hepatocellular carcinoma (HCC). The SEPT9 gene is a key regulator of cell division and tumor suppressor whose hypermethylation is associated with liver carcinogenesis. The primary aim of this study was to evaluate the diagnostic accuracy of a P...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Oussalah, Abderrahim, Rischer, Susann, Bensenane, Mouni, Conroy, Guillaume, Filhine-Tresarrieu, Pierre, Debard, Renée, Forest-Tramoy, Denise, Josse, Thomas, Reinicke, Dana, Garcia, Matthieu, Luc, Amandine, Baumann, Cédric, Ayav, Ahmet, Laurent, Valérie, Hollenbach, Marcus, Ripoll, Cristina, Guéant-Rodriguez, Rosa-Maria, Namour, Fares, Zipprich, Alexander, Fleischhacker, Michael, Bronowicki, Jean-Pierre, Guéant, Jean-Louis
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952996/
https://ncbi.nlm.nih.gov/pubmed/29627389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.03.029
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