A review of connectivity map and computational approaches in pharmacogenomics

Large-scale perturbation databases, such as Connectivity Map (CMap) or Library of Integrated Network-based Cellular Signatures (LINCS), provide enormous opportunities for computational pharmacogenomics and drug design. A reason for this is that in contrast to classical pharmacology focusing at one t...

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Publicat a:Brief Bioinform
Autors principals: Musa, Aliyu, Ghoraie, Laleh Soltan, Zhang, Shu-Dong, Glazko, Galina, Yli-Harja, Olli, Dehmer, Matthias, Haibe-Kains, Benjamin, Emmert-Streib, Frank
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952941/
https://ncbi.nlm.nih.gov/pubmed/28069634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw112
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