Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin

The endonuclease G gene (Endog), which codes for a mitochondrial nuclease, was identified as a determinant of cardiac hypertrophy. How ENDOG controls cardiomyocyte growth is still unknown. Thus, we aimed at finding the link between ENDOG activity and cardiomyocyte growth. Endog deficiency induced re...

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Publicado en:Redox Biol
Autores principales: Blasco, Natividad, Cámara, Yolanda, Núñez, Estefanía, Beà, Aida, Barés, Gisel, Forné, Carles, Ruíz-Meana, Marisol, Girón, Cristina, Barba, Ignasi, García-Arumí, Elena, García-Dorado, David, Vázquez, Jesús, Martí, Ramon, Llovera, Marta, Sanchis, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952880/
https://ncbi.nlm.nih.gov/pubmed/29502044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.02.021
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