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A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
Loss of first-phase insulin release is an early pathogenic feature of type 2 diabetes (T2D). Various mouse models exist to study T2D; however, few recapitulate the early β-cell defects seen in humans. We sought to develop a nongenetic mouse model of T2D that exhibits reduced first-phase insulin secr...
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| Publicado no: | J Diabetes Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5952555/ https://ncbi.nlm.nih.gov/pubmed/29854823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6106051 |
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