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Ocrelizumab: a new milestone in multiple sclerosis therapy

B cells play a central role in the pathogenesis of multiple sclerosis (MS): they are involved in the activation of pro-inflammatory T cells, secretion of pro-inflammatory cytokines and production of autoantibodies directed against myelin. Hence, the use of B cell-depleting monoclonal antibodies as t...

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Dettagli Bibliografici
Pubblicato in:Ther Adv Neurol Disord
Autori principali: Mulero, Patricia, Midaglia, Luciana, Montalban, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952271/
https://ncbi.nlm.nih.gov/pubmed/29774057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756286418773025
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