Every enhancer works with every promoter for all the combinations tested: could new regulatory pathways evolve by enhancer shuffling?

The promoters and enhancers of cell type-specific genes are often conserved in evolution, and hence one might expect that a given enhancer has evolved to work best with its own promoter. While this expectation may be realized in some cases, we have not found evidence for it. A total of 27 combinatio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Gene Expr
Main Authors: Kermekchiev, Milko, Pettersson, Monica, Hamkalo, Barbara A., Schaffner, Walter
Format: Artigo
Sprog:Inglês
Udgivet: Cognizant Communication Corporation 2018
Fag:
Mini-Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952201/
https://ncbi.nlm.nih.gov/pubmed/1668145
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker