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Preferential distribution of active RNA polymerase II molecules in the nuclear periphery

We have combined immunogold labeling with the Miller spreading technique in order to localize proteins at the electron microscope (EM) level in whole mount nuclei from mouse and human fibroblasts. Anti-histone HI antibody labels nuclei uniformly, indicating that the nuclear interior is accessible to...

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Pubblicato in:Gene Expr
Autori principali: Clark, Robert F., Cho, Ken W. J., Weinmann, Roberto, Hamkalo, Barbara A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952200/
https://ncbi.nlm.nih.gov/pubmed/1668144
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