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Identification of H209 as Essential for pH 8-Triggered Receptor-Independent Syncytium Formation by S Protein of Mouse Hepatitis Virus A59

The spike glycoprotein (S) of murine coronavirus mouse hepatitis virus (MHV) strain A59 uses murine carcinoembryonic antigen-related cell adhesion molecule 1a as its receptor for cell entry, but S protein can also be triggered in the absence of receptor by pH 8.0 alone at 37°C. The mechanism by whic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Pei, Shan, Yiwei, Zheng, Wangliang, Ou, Xiuyuan, Mi, Dan, Mu, Zhixia, Holmes, Kathryn V., Qian, Zhaohui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952161/
https://ncbi.nlm.nih.gov/pubmed/29514915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00209-18
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