Extracellular Conformational Changes in the Capsid of Human Papillomaviruses Contribute to Asynchronous Uptake into Host Cells

Human papillomavirus 16 (HPV16) is the leading cause of cervical cancer. For initial infection, HPV16 utilizes a novel endocytic pathway for host cell entry. Unique among viruses, uptake occurs asynchronously over a protracted period of time, with half-times between 9 and 12 h. To trigger endocytic...

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Bibliographic Details
Published in:J Virol
Main Authors: Becker, Miriam, Greune, Lilo, Schmidt, M. Alexander, Schelhaas, Mario
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952151/
https://ncbi.nlm.nih.gov/pubmed/29593032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02106-17
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