A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus Infection

Humanized mouse model generated by grafting primary human hepatocytes (PHHs) to immunodeficient mouse has contributed invaluably to understanding the pathogenesis of hepatitis B virus (HBV). However, the source of PHHs is limited, which necessitates the search for alternatives. Recently, hepatocyte-...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yuan, Lunzhi, Liu, Xuan, Zhang, Liang, Li, Xiaoling, Zhang, Yali, Wu, Kun, Chen, Yao, Cao, Jiali, Hou, Wangheng, Zhang, Jun, Zhu, Hua, Yuan, Quan, Tang, Qiyi, Cheng, Tong, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952038/
https://ncbi.nlm.nih.gov/pubmed/29867819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00908
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