The extent of liver injury determines hepatocyte fate toward senescence or cancer

It is well known that induction of hepatocyte senescence could inhibit the development of hepatocellular carcinoma (HCC). Until now, it is still unclear how the degree of liver injury dictates hepatocyte senescence and carcinogenesis. In this study, we investigated whether the severity of injury det...

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Publicado no:Cell Death Dis
Main Authors: Wang, Chao, Chen, Wen-Jian, Wu, Ying-Fu, You, Pu, Zheng, Shang-Yong, Liu, Chang-Cheng, Xiang, Dao, Wang, Min-Jun, Cai, Yong-Chao, Zhao, Qing-Hui, Borjigin, Uyunbilig, Liu, Wei, Xiong, Wu-Jun, Wangensteen, Kirk J., Wang, Xin, Liu, Zhong-Min, He, Zhi-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951829/
https://ncbi.nlm.nih.gov/pubmed/29760381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0622-x
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