An NF90/NF110-mediated feedback amplification loop regulates dicer expression and controls ovarian carcinoma progression

Reduced expression of DICER, a key enzyme in the miRNA pathway, is frequently associated with aggressive, invasive disease, and poor survival in various malignancies. Regulation of DICER expression is, however, poorly understood. Here, we show that NF90/NF110 facilitates DICER expression by controll...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Barbier, Jérôme, Chen, Xin, Sanchez, Gabriel, Cai, Muyan, Helsmoortel, Marion, Higuchi, Takuma, Giraud, Pierre, Contreras, Xavier, Yuan, Gangjun, Feng, Zihao, Nait-Saidi, Rima, Deas, Olivier, Bluy, Lisa, Judde, Jean-Gabriel, Rouquier, Sylvie, Ritchie, William, Sakamoto, Shuji, Xie, Dan, Kiernan, Rosemary
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951825/
https://ncbi.nlm.nih.gov/pubmed/29563539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0016-8
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