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Assembly of the yeast mitoribosome large subunit proceeds by the hierarchical incorporation of protein clusters and modules on the inner membrane

Mitoribosomes are specialized for the synthesis of hydrophobic membrane proteins encoded by mitochondrial DNA, all essential for oxidative phosphorylation. Despite their linkage to human mitochondrial diseases and the recent cryo-EM reconstruction of yeast and mammalian mitoribosomes, how they are a...

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Detalles Bibliográficos
Publicado en:Cell Metab
Autores principales: Zeng, Rui, Smith, Erin, Barrientos, Antoni
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951612/
https://ncbi.nlm.nih.gov/pubmed/29514071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.01.012
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