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Assembly of the yeast mitoribosome large subunit proceeds by the hierarchical incorporation of protein clusters and modules on the inner membrane

Mitoribosomes are specialized for the synthesis of hydrophobic membrane proteins encoded by mitochondrial DNA, all essential for oxidative phosphorylation. Despite their linkage to human mitochondrial diseases and the recent cryo-EM reconstruction of yeast and mammalian mitoribosomes, how they are a...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Zeng, Rui, Smith, Erin, Barrientos, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951612/
https://ncbi.nlm.nih.gov/pubmed/29514071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.01.012
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