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Gold-catalyzed formal [4π + 2π]-cycloadditions of propiolate derivatives with unactivated nitriles

Gold-catalyzed hetero-[4π + 2π]-cycloadditions of tert-butyl propiolates with unactivated nitriles are described; the resulting 6H-1,3-oxazin-6-ones are not easily accessible via conventional methods. This new finding enables a one-pot gold-catalyzed synthesis of highly substituted pyridines through...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Karad, Somnath Narayan, Chung, Wei-Kang, Liu, Rai-Shung
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950837/
https://ncbi.nlm.nih.gov/pubmed/29861918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01950h
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