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Chiral phosphine-catalyzed tunable cycloaddition reactions of allenoates with benzofuranone-derived olefins for a highly regio-, diastereo- and enantioselective synthesis of spiro-benzofuranones

The first regioselective catalytic asymmetric [3 + 2] cycloaddition of benzofuranone-derived olefins with allenoates and substituted allenoates has been developed in the presence of (R)-SITCP, affording different functionalized 3-spirocyclopentene benzofuran-2-ones in good yields with high enantiose...

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Publicado en:Chem Sci
Autores principales: Wang, De, Wang, Guo-Peng, Sun, Yao-Liang, Zhu, Shou-Fei, Wei, Yin, Zhou, Qi-Lin, Shi, Min
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950759/
https://ncbi.nlm.nih.gov/pubmed/29861963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03135d
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